SCHEMBL21274792

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11486845	0.89	SMN1; SMN2 (0.85)	HPGDALDH1A1SMN1; SMN2PARP10SRD5A2
	SCHEMBL458926	0.88	ALDH1A1 (0.61)	HPGDALDH1A1SMN1; SMN2SRD5A2CA1
	SCHEMBL5612757	0.85	HPGD (0.85)	HPGDALDH1A1SMN1; SMN2PARP15PARP10
	Ethane SCHEMBL11219716	0.83	PARP10 (0.72)	HPGDALDH1A1SMN1; SMN2PARP15PARP10
	SCHEMBL22281	0.83	PARP10 (0.78)	HPGDALDH1A1PARP15PARP10SRD5A2
	SCHEMBL5581520	0.83	PARP10 (0.78)	HPGDALDH1A1PARP15PARP10SRD5A2
	SCHEMBL766069	0.83	PARP10 (0.78)	HPGDALDH1A1PARP15PARP10SRD5A2
	Terephthalic Acid SCHEMBL9861713	0.83	PARP10 (0.78)	HPGDALDH1A1PARP15PARP10SRD5A2
	SCHEMBL5612755	0.83	HPGD (0.81)	HPGDALDH1A1SMN1; SMN2PARP15PARP10
	SCHEMBL5937241	0.82	CSNK2A1 (0.62)	HPGDALDH1A1SMN1; SMN2MAPTRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.