Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | PTPRF | P10586 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5072717 | 0.89 | TSHR (0.68) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL11418643 | 0.84 | TSHR (0.77) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL5072718 | 0.83 | TSHR (0.60) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL5353532 | 0.83 | TSHR (0.56) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL15264948 | 0.83 | TSHR (0.81) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL15264951 | 0.83 | TSHR (0.60) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL5575276 | 0.82 | ALDH1A1 (0.70) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL28048856 | 0.81 | TSHR (0.68) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL5076639 | 0.80 | TSHR (0.53) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL29287656 | 0.80 | TSHR (0.53) | TSHRTDP1L3MBTL1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10385010-B1 | Expedient synthesis of oseltamivir and related compounds via direct olefin diazidation-diamidation reaction | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2019-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10385010-B1 | Expedient synthesis of oseltamivir and related compounds via direct olefin diazidation-diamidation reaction | TALDO1, DDO, DAO | TSHR 2270/4885TDP1 2167/4885L3MBTL1 3248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.