Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2128292 | 0.98 | MAPT (0.48) | MAPTTLR8KDM4EALDH1A1HPGD | |
| SCHEMBL2126066 | 0.93 | NCEH1 (0.43) | MAPTTLR8KDM4EALDH1A1HPGD | |
| SCHEMBL2127621 | 0.88 | ALDH1A1 (0.47) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5116260 | 0.86 | MAPT (0.55) | MAPTTLR8KDM4EALDH1A1HPGD | |
| SCHEMBL8379349 | 0.86 | MAPT (0.55) | MAPTTLR8KDM4EALDH1A1HPGD | |
| SCHEMBL16267023 | 0.86 | MAPT (0.55) | MAPTTLR8KDM4EALDH1A1HPGD | |
| SCHEMBL16267095 | 0.86 | MAPT (0.55) | MAPTTLR8KDM4EALDH1A1HPGD | |
| SCHEMBL16267503 | 0.86 | MAPT (0.55) | MAPTTLR8KDM4EALDH1A1HPGD | |
| SCHEMBL299862 | 0.84 | MAPT (0.53) | MAPTTLR8KDM4EALDH1A1HPGD | |
| SCHEMBL11236029 | 0.83 | CYP1A2 (0.36) | MAPTKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120096878-A1 | Refrigeration Circuit and Method for Improving Same | SANDEN CORPORATION (JP) | 2012-04-26 | — | — | US | disclosed |
| EP-2444469-A1 | REFRIGERATION CIRCUIT AND METHOD FOR IMPROVING SAME | Sanden Corporation (JP) | 2012-04-25 | — | — | EP | disclosed |