SCHEMBL5116260

SCHEMBL5116260

CCCCCCc1c2ccccc2cc2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.55
HTR2A P28223 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TLR8 Q9NR97 4/20 0.48
KCNH2 Q12809 1/20 0.46
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
HPGD P15428 2/20 0.45
HSD17B10 Q99714 1/20 0.45
GAA P10253 1/20 0.44
CTSV O60911 1/20 0.44
CTSL P07711 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8379349 1.00 MAPT (0.55) MAPTHTR2AL3MBTL1TLR8KCNH2
SCHEMBL16267095 1.00 MAPT (0.55) MAPTHTR2AL3MBTL1TLR8KCNH2
SCHEMBL16267023 1.00 MAPT (0.55) MAPTHTR2AL3MBTL1TLR8KCNH2
SCHEMBL16267503 1.00 MAPT (0.55) MAPTHTR2AL3MBTL1TLR8KCNH2
SCHEMBL299862 0.98 MAPT (0.53) MAPTHTR2AL3MBTL1TLR8KDM4E
SCHEMBL7915017 0.92 HTR2A (0.52) MAPTHTR2AL3MBTL1TLR8KDM4E
SCHEMBL7874386 0.90 HTR2A (0.58) MAPTHTR2AL3MBTL1KDM4EALDH1A1
SCHEMBL7877797 0.90 HTR2A (0.58) MAPTHTR2AL3MBTL1KDM4EALDH1A1
SCHEMBL29104758 0.89 RORA (0.47) MAPTHTR2AKDM4EALDH1A1HSD17B10
SCHEMBL29104770 0.89 RORA (0.47) MAPTHTR2AKDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102344404-A Melamine fluorescent sensor material based on phthalimide UNIV NANJING POSTS & TELECOMM 2012-02-08 CN claimed
US-11685702-B2 Method for producing arene compounds and arene compounds produced by the same JSI SILICONE CO. (KR) 2023-06-27 US disclosed
US-20210188739-A1 METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME JSI SILICONE CO. (KR) 2021-06-24 US disclosed
US-9067857-B2 Fluorine-containing aromatic compound and manufacturing method therefor ASAHI GLASS COMPANY, LIMITED (JP) 2015-06-30 US disclosed
CN-102807534-B Organic semiconductor material and preparation method thereof OCEANS KING LIGHTING SCIENCE 2015-04-22 CN disclosed
EP-1907511-B1 METHOD FOR DEGRADING POLYCYCLIC AROMATIC HYDROCARBONS BY USING AN IMMOBILIZED HEMOPROTEIN TOTAL MARKETING SERVICES (FR) 2015-01-14 EP disclosed
US-20140357906-A1 FLUORINE-CONTAINING AROMATIC COMPOUND AND MANUFACTURING METHOD THEREFOR AGC Inc. (JP) 2014-12-04 US disclosed
CN-102653678-B Conduction cavity type electroluminescent material and preparation method and application thereof OCEANS KING LIGHTING SCIENCE 2014-11-05 CN disclosed
CN-104114522-A Fluorine-containing aromatic compound and manufacturing method therefor ASAHI GLASS CO LTD 2014-10-22 CN disclosed
CN-102464978-B Conductive cavity-type blue electroluminescent material and preparation method and application thereof OCEANS KING LIGHTING SCIENCE 2014-06-11 CN disclosed
CN-102807534-A Organic semiconductor material and preparation method thereof OCEANS KING LIGHTING SCIENCE 2012-12-05 CN disclosed
CN-102653678-A Conduction cavity type electroluminescent material and preparation method and application thereof OCEANS KING LIGHTING SCIENCE 2012-09-05 CN disclosed
CN-102464978-A Conductive cavity-type blue electroluminescent material and preparation method and application thereof OCEANS KING LIGHTING SCIENCE 2012-05-23 CN disclosed
CN-102344404-A Melamine fluorescent sensor material based on phthalimide UNIV NANJING POSTS & TELECOMM 2012-02-08 CN disclosed
EP-1907511-A2 METHOD FOR DEGRADING POLYCYCLIC AROMATIC HYDROCARBONS BY USING AN IMMOBILIZED HEMOPROTEIN Total France (FR) 2008-04-09 EP disclosed
WO-2007006925-A2 METHOD FOR DEGRADING POLYCYCLIC AROMATIC HYDROCARBONS BY USING AN IMMOBILIZED HEMOPROTEIN TOTAL FRANCE (FR) 2007-01-18 WO disclosed
US-4131646-A Preparation of hydrogen peroxide from dihydroanthracene hydroperoxides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-12-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210188739-A1 METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME PFAS, FRK, AGPAT2 MAPT 3934/4885HTR2A 2820/4885L3MBTL1 4367/4885
US-20140357906-A1 FLUORINE-CONTAINING AROMATIC COMPOUND AND MANUFACTURING METHOD THEREFOR AFF1, AFF2, AFF4 MAPT 2140/4885HTR2A 3343/4885L3MBTL1 2967/4885
US-11685702-B2 Method for producing arene compounds and arene compounds produced by the same PFAS, FRK, AGPAT2 MAPT 3934/4885HTR2A 2820/4885L3MBTL1 4367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.