Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 7/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1355384 | 0.86 | CHRNB2 (0.34) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL16752051 | 0.86 | CHRNB2 (0.34) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL869104 | 0.84 | PLA2G1B (0.33) | — | |
| SCHEMBL25575374 | 0.79 | — | — | |
| SCHEMBL14735285 | 0.79 | SIGMAR1 (0.44) | CHRNB2CHRNA4CHRNB4SIGMAR1CHRNA3 | |
| SCHEMBL232018 | 0.79 | — | — | |
| SCHEMBL1250787 | 0.78 | CHRNB2 (0.40) | CHRNB2CHRNA4CHRNB4SIGMAR1CHRNA3 | |
| SCHEMBL16752081 | 0.74 | CHRNB2 (0.34) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL10682726 | 0.74 | — | — | |
| SCHEMBL7248741 | 0.73 | CHRNB2 (0.33) | CHRNB2CHRNA4CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215148-B1 | ORGANOPOLYSILOXANES COMPRISING QUATERNARY AMMONIUM GROUPS, THE PRODUCTION AND USE THEREOF | WACKER CHEMIE AG (DE) | 2012-04-25 | — | — | EP | disclosed |
| US-20100243944-A1 | ORGANOPOLYSILOXANES CONTAINING QUATERNARY AMMONIUM GROUPS, THE PRODUCTION AND USE THEREOF | WACKER CHEMIE AG (DE) | 2010-09-30 | — | — | US | disclosed |