Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PDE8B | O95263 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2737908 | 1.00 | HPGD (0.39) | HPGDGAAPDE8BALDH1A1L3MBTL1 | |
| SCHEMBL2737942 | 0.90 | PDE8B (0.40) | HPGDGAAPDE8BALDH1A1L3MBTL1 | |
| SCHEMBL2737925 | 0.88 | GPR119 (0.38) | ALDH1A1L3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL2737945 | 0.88 | ABCB1 (0.41) | HPGDGAAPDE8BALDH1A1L3MBTL1 | |
| SCHEMBL22175827 | 0.87 | PDE8B (0.37) | HPGDGAAPDE8BALDH1A1L3MBTL1 | |
| SCHEMBL22164263 | 0.87 | PDE8B (0.37) | HPGDGAAPDE8BALDH1A1L3MBTL1 | |
| SCHEMBL2737976 | 0.86 | PDE8B (0.39) | HPGDGAAPDE8BALDH1A1L3MBTL1 | |
| SCHEMBL2737944 | 0.85 | ABCB1 (0.41) | HPGDPDE8BALDH1A1L3MBTL1MEN1 | |
| SCHEMBL15317015 | 0.85 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL21279696 | 0.85 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838900-B1 | COMPOUNDS AND METHODS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2019-08-21 | — | — | EP | disclosed |