Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 7/20 | 0.53 |
| ▸ | CLK1 | P49759 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2127287 | 0.88 | ALDH1A3 (0.58) | ALDH1A3CLK1DYRK1ANPC1RAB9A | |
| SCHEMBL2129493 | 0.85 | ALDH1A1 (0.55) | ALDH1A3NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2127120 | 0.84 | NPC1 (0.71) | ALDH1A3CLK1DYRK1ANPC1RAB9A | |
| SCHEMBL27731953 | 0.82 | CLK1 (0.59) | ALDH1A3CLK1DYRK1ANPC1RAB9A | |
| SCHEMBL2128357 | 0.81 | NPC1 (0.57) | ALDH1A3CLK1DYRK1ANPC1RAB9A | |
| SCHEMBL1691332 | 0.80 | DYRK1A (0.60) | ALDH1A3CLK1DYRK1ANPC1RAB9A | |
| SCHEMBL22906630 | 0.76 | APP (0.73) | ALDH1A3CLK1DYRK1ANPC1RAB9A | |
| SCHEMBL2129038 | 0.76 | NPC1 (0.63) | ALDH1A3NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2127192 | 0.75 | ALDH1A1 (0.67) | ALDH1A3CLK1DYRK1ANPC1RAB9A | |
| SCHEMBL2127074 | 0.74 | NPC1 (0.56) | ALDH1A3NPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129375-B1 | IMIDAZO[1,2-A]PYRIDINES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2012-04-25 | — | — | EP | claimed |