Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21280449 | 0.85 | HMGCR (0.34) | HMGCR | |
| SCHEMBL16575420 | 0.76 | HMGCR (0.38) | HMGCRKDM4EALDH1A1 | |
| SCHEMBL26246478 | 0.76 | KDM4E (0.36) | KDM4E | |
| SCHEMBL21280424 | 0.76 | HMGCR (0.53) | HMGCRALDH1A1 | |
| SCHEMBL12716286 | 0.74 | RAPGEF4 (0.32) | — | |
| SCHEMBL28101513 | 0.71 | KDM4E (0.33) | HMGCRKDM4EALDH1A1 | |
| SCHEMBL21280140 | 0.71 | — | — | |
| SCHEMBL13525418 | 0.70 | HMGCR (0.36) | HMGCRKDM4EALDH1A1 | |
| SCHEMBL21386521 | 0.68 | NPSR1 (0.39) | HMGCRALDH1A1 | |
| SCHEMBL13335373 | 0.68 | HMGCR (0.33) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2821402-B1 | NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | ASTELLAS PHARMA INC (JP) | 2019-08-21 | — | — | EP | disclosed |