Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 5/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21280285 | 0.85 | HMGCR (0.32) | HMGCR | |
| SCHEMBL16575420 | 0.73 | HMGCR (0.38) | HMGCR | |
| SCHEMBL10985455 | 0.71 | GCGR (0.38) | GCGR | |
| SCHEMBL15725748 | 0.68 | PDE4A (0.38) | HMGCR | |
| SCHEMBL10989730 | 0.67 | GCGR (0.41) | GCGR | |
| SCHEMBL13525418 | 0.67 | HMGCR (0.36) | HMGCRMAOA | |
| SCHEMBL21386521 | 0.66 | NPSR1 (0.39) | HMGCRMAOA | |
| SCHEMBL14724344 | 0.66 | SHBG (0.36) | — | |
| SCHEMBL7189577 | 0.66 | HMGCR (0.53) | HMGCR | |
| SCHEMBL18924281 | 0.66 | HMGCR (0.53) | HMGCRMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2821402-B1 | NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | ASTELLAS PHARMA INC (JP) | 2019-08-21 | — | — | EP | disclosed |