Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.50 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.46 |
| ▸ | TNF | P01375 | 3/20 | 0.46 |
| ▸ | IL1B | P01584 | 2/20 | 0.46 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864613 | 0.81 | CRBN (0.62) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL22737366 | 0.77 | CRBN (0.67) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL17724153 | 0.75 | CRBN (0.67) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL17724152 | 0.75 | CRBN (0.67) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL17724079 | 0.75 | CRBN (0.67) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL22199378 | 0.74 | CRBN (0.47) | CRBNDDB1IKZF3TNFALDH1A1 | |
| SCHEMBL19310169 | 0.71 | CRBN (0.47) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL30585102 | 0.71 | CRBN (0.47) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL21281328 | 0.70 | CYP19A1 (0.35) | CRBNDDB1 | |
| SCHEMBL20458996 | 0.69 | CRBN (0.65) | CRBNDDB1IKZF3TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3527210-A1 | COMPOSITION, APPLICATION THEREOF AND TREATMENT METHOD | Kangpu Biopharmaceuticals, Ltd. (CN) | 2019-08-21 | — | — | EP | disclosed |