Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | GFER | P55789 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2537577 | 0.99 | MAPT (0.36) | MAPTGFERALDH1A1KDM4EGAA | |
| Hydrochloric Acid SCHEMBL6331452 | 0.99 | MAPT (0.36) | MAPTGFERALDH1A1KDM4EGAA | |
| Hydrochloric Acid SCHEMBL6159442 | 0.99 | MAPT (0.37) | MAPTGFERALDH1A1KDM4EGAA | |
| Hydrochloric Acid SCHEMBL1154193 | 0.97 | MAPT (0.36) | MAPTGFERALDH1A1KDM4EGAA | |
| Hydrochloric Acid SCHEMBL5254010 | 0.90 | KDM4E (0.31) | MAPTGFERALDH1A1KDM4EGAA | |
| SCHEMBL2127393 | 0.84 | RAD52 (0.41) | MAPTKDM4EGAAPTK2BHTT | |
| Hydrochloric Acid SCHEMBL2540311 | 0.83 | RAD52 (0.40) | MAPTKDM4EGAATHRBRAD52 | |
| Hydrochloric Acid SCHEMBL6328982 | 0.82 | RAD52 (0.40) | MAPTKDM4EGAARAD52HRH3 | |
| SCHEMBL2928431 | 0.82 | MAPT (0.33) | MAPTGFERALDH1A1KDM4EGAA | |
| SCHEMBL2128163 | 0.81 | MEN1 (0.45) | MAPTALDH1A1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1348695-B1 | Derivatives of paraphenylene diamine with pyrrolidine groups substituted by cationic radicals and their use for dyeing keratinic fibre | OREAL (FR) | 2012-04-25 | — | — | EP | claimed |
| US-8002847-B2 | Composition for oxidation dyeing keratin fibres comprising a cationic cellulose ether, a weakly oxyethylenated sorbitan fatty acid ester and oxidation dyes | L 'OREAL S.A. (FR) | 2011-08-23 | — | — | US | claimed |
| US-20100275388-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | L'OREAL S.A. (FR) | 2010-11-04 | — | — | US | claimed |
| EP-1428515-B1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a surfactant; methods and uses | OREAL (FR) | 2008-07-02 | — | — | EP | claimed |
| EP-1834972-A1 | Manufacture, using NCO functional carboxylic acid and carbamoyl halogenides, of isocyanate functional prepolymers which are stable during storage | Bayer MaterialScience AG (DE) | 2007-09-19 | — | — | EP | claimed |
| EP-1428514-B1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, a tertiary paraphenylenediamine and a benzomorpholine coupler; method and use | OREAL (FR) | 2007-09-19 | — | — | EP | claimed |
| EP-1559412-A1 | Keratinous fibre-dyeing composition containing an alcohol oxydase and a cationic oxidation base | L'OREAL (FR) | 2005-08-03 | — | — | EP | claimed |
| US-20040221400-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a monosaccharide or disaccharide, processes and uses | L'OREAL (FR) | 2004-11-11 | — | — | US | claimed |
| EP-1428514-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, a tertiary paraphenylenediamine and a benzomorpholine coupler; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428506-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a polymere containing a fatty chain; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428507-A1 | Dyeing composition containing a tertiary cationic paraphenylendiamine and an organic diacid, process and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428516-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a polyol ester; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428508-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a monosaccharide or disaccharide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428513-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a opacifying or pearlescent agent; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428509-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a polyol; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428512-A1 | Dyeing composition containing a tertiary cationic paraphenylendiamine and a paraaminophenol, process and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428505-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a cationic direct dye containing a heterocyclic group ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428511-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a cationic polymer; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1348695-A1 | Derivatives of paraphenylene diamine with pyrrolidine groups substituted by cationic radicals and their use for dyeing keratinic fibre | L'OREAL (FR) | 2003-10-01 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040221400-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a monosaccharide or disaccharide, processes and uses | KRT18, DPM1, DSG1 | MAPT 1357/4885GFER 4300/4885ALDH1A1 1189/4885 |
| US-20100275388-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | KRT18, KRTCAP2, FASN | MAPT 687/4885GFER 478/4885ALDH1A1 1792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.