Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 3/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21282159 | 0.86 | FYN (0.49) | MEN1KMT2APABPC1PIK3CAMAPK8 | |
| SCHEMBL21282210 | 0.86 | KMT2A (0.47) | MEN1KMT2APABPC1PIK3CAMAPK8 | |
| SCHEMBL21282158 | 0.85 | FYN (0.50) | MEN1KMT2APABPC1PIK3CAMAPK8 | |
| SCHEMBL21282189 | 0.85 | MEN1 (0.46) | MEN1KMT2APABPC1PIK3CAMAPK8 | |
| SCHEMBL21282214 | 0.81 | PIK3CA (0.47) | MEN1KMT2APABPC1PIK3CAMAPK8 | |
| SCHEMBL21282217 | 0.80 | MEN1 (0.69) | MEN1KMT2APABPC1PIK3CAMAPK8 | |
| SCHEMBL21282160 | 0.79 | MAPT (0.44) | MEN1KMT2APABPC1PIK3CAMAPK8 | |
| SCHEMBL21282164 | 0.79 | PIK3CA (0.43) | MEN1KMT2APABPC1PIK3CAMAPK8 | |
| SCHEMBL21282177 | 0.76 | MEN1 (0.48) | MEN1KMT2APABPC1PIK3CAMAPK8 | |
| SCHEMBL7270843 | 0.75 | APP (0.41) | KMT2ACDK4CCND1CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190256492-A1 | ALPHA-SYNUCLEIN LIGANDS | WASHINGTON UNIVERSITY (US) | 2019-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256492-A1 | ALPHA-SYNUCLEIN LIGANDS | SNCA, PARK7, LRRK2 | MEN1 4044/4885KMT2A 4633/4885PABPC1 1798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.