Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 7/20 | 0.34 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | ITK | Q08881 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2128491 | 0.79 | GSK3A (0.51) | — | |
| SCHEMBL22496896 | 0.79 | BTK (0.41) | BTK | |
| SCHEMBL19665668 | 0.78 | PIN1 (0.42) | KMT2AL3MBTL1 | |
| SCHEMBL22496836 | 0.77 | JAK3 (0.44) | BTK | |
| SCHEMBL22496751 | 0.77 | JAK3 (0.42) | EGFRBTK | |
| SCHEMBL17536544 | 0.77 | ALDH1A1 (0.38) | HCRTR2HCRTR1ALDH1A1 | |
| SCHEMBL22496736 | 0.76 | JAK3 (0.38) | BTK | |
| SCHEMBL22496978 | 0.76 | JAK3 (0.32) | BTK | |
| SCHEMBL26628895 | 0.76 | MAPK3 (0.40) | HCRTR2HCRTR1 | |
| SCHEMBL22496852 | 0.75 | JAK3 (0.31) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2442809-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | Vertex Pharmaceuticals Incorporated (US) | 2012-04-25 | — | — | EP | disclosed |