SCHEMBL21283929

SCHEMBL21283929

C=CCOP(=O)(OCCC#N)OC1C(F)[C@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)O[C@@H]1COP(=S)(OCCC#N)OC1C(F)[C@@H](CO)O[C@H]1n1ccc(=O)[nH]c1=O

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ RNASEL Q05823 4/20 0.39
▸ P2RY2 P41231 3/20 0.36
▸ P2RY4 P51582 2/20 0.36
▸ P2RY12 Q9H244 8/20 0.36
▸ P2RY14 Q15391 1/20 0.35
▸ P2RY6 Q15077 2/20 0.35
▸ P2RY1 P47900 1/20 0.35
▸ PRMT6 Q96LA8 1/20 0.35
▸ DNPH1 O43598 1/20 0.34
▸ P2RX3 P56373 1/20 0.34
▸ P2RX4 Q99571 1/20 0.34
▸ P2RX2 Q9UBL9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20778035 1.00 RNASEL (0.39) RNASELP2RY2P2RY4P2RY12P2RY14
SCHEMBL30292623 1.00 RNASEL (0.39) RNASELP2RY2P2RY4P2RY12P2RY14
SCHEMBL23621433 1.00 RNASEL (0.39) RNASELP2RY2P2RY4P2RY12P2RY14
SCHEMBL26435596 1.00 RNASEL (0.39) RNASELP2RY2P2RY4P2RY12P2RY14
SCHEMBL22375444 0.97 RNASEL (0.40) RNASELP2RY2P2RY4P2RY12P2RY14
SCHEMBL20778026 0.91 RNASEL (0.45) RNASELP2RY2P2RY4P2RY12P2RY14
SCHEMBL26442453 0.91 RNASEL (0.45) RNASELP2RY2P2RY4P2RY12P2RY14
SCHEMBL30292621 0.91 RNASEL (0.45) RNASELP2RY2P2RY4P2RY12P2RY14
SCHEMBL26294855 0.91 RNASEL (0.38) RNASELP2RY2P2RY4P2RY12P2RY14
SCHEMBL26294872 0.91 RNASEL (0.38) RNASELP2RY2P2RY4P2RY12P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210205347-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE INVOX PHARMA LIMITED (GB) 2021-07-08 — — US disclosed
WO-2019161171-A1 NANOPARTICLE FORMULATIONS OF STING AGONISTS SPEROVIE BIOSCIENCES, INC. (US) 2019-08-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210205347-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE STING1, MAVS, IRF3 RNASEL 1374/4885P2RY2 1016/4885P2RY4 1082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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