Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 5/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.30 |
| ▸ | GPR183 | P32249 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21343925 | 0.92 | BTK (0.31) | — | |
| SCHEMBL24092256 | 0.92 | CYP2D6 (0.34) | HIF1ACYP1A2CYP2C9TSHRMEN1 | |
| SCHEMBL21285100 | 0.91 | HIF1A (0.33) | HIF1ACYP1A2CYP2C9TSHRMEN1 | |
| SCHEMBL21285149 | 0.91 | — | — | |
| SCHEMBL23748403 | 0.91 | — | — | |
| SCHEMBL21285251 | 0.90 | CYP2D6 (0.31) | HIF1ACYP1A2CYP2C9TSHRMEN1 | |
| SCHEMBL24426506 | 0.90 | — | — | |
| SCHEMBL21285249 | 0.90 | HIF1A (0.31) | HIF1ACYP1A2CYP2C9TSHRMEN1 | |
| SCHEMBL21285253 | 0.89 | HIF1A (0.30) | HIF1ACYP1A2CYP2C9TSHRMEN1 | |
| SCHEMBL22907824 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11542235-B2 | Herbicidal 3-azaspiro[5.5] undecane-8, 10-dione compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2023-01-03 | — | — | US | disclosed |
| US-11542235-B2 | Herbicidal 3-azaspiro[5.5] undecane-8, 10-dione compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2023-01-03 | — | — | US | disclosed |
| EP-3762378-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-18 | — | — | EP | disclosed |
| EP-3752490-B1 | HERBICIDAL 3-AZASPIRO[5.5]UNDECANE-8,10-DIONE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-12-15 | — | — | EP | disclosed |
| US-20210139432-A1 | HERBICIDAL 3- AZASPIRO[5.5] UNDECANE-8, 10-DIONE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-05-13 | — | — | US | disclosed |
| US-20210139432-A1 | HERBICIDAL 3- AZASPIRO[5.5] UNDECANE-8, 10-DIONE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-05-13 | — | — | US | disclosed |
| WO-2021018826-A1 | CYCLIC DIONES AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2021-02-04 | — | — | WO | disclosed |
| WO-2019170745-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-12 | — | — | WO | disclosed |
| WO-2019158666-A1 | HERBICIDAL 3-AZASPIRO[5.5]UNDECANE-8,10-DIONE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139432-A1 | HERBICIDAL 3- AZASPIRO[5.5] UNDECANE-8, 10-DIONE COMPOUNDS | DDT, DECR1, DHRS9 | HIF1A 3139/4885CYP1A2 35/4885CYP2C9 377/4885 |
| US-11542235-B2 | Herbicidal 3-azaspiro[5.5] undecane-8, 10-dione compounds | DDT, DECR1, DHRS9 | HIF1A 3139/4885CYP1A2 35/4885CYP2C9 377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.