Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 3/20 | 0.38 |
| ▸ | FLT3 | P36888 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21274501 | 0.83 | GPR119 (0.42) | TP53PARP1JAK2 | |
| SCHEMBL21274200 | 0.83 | GPR119 (0.42) | TP53PARP1JAK2 | |
| SCHEMBL22801948 | 0.83 | GPR119 (0.42) | TP53PARP1JAK2 | |
| SCHEMBL21285548 | 0.83 | PARP1 (0.35) | PARP1 | |
| SCHEMBL22823000 | 0.83 | KMT2A (0.43) | KMT2AMEN1MAPTSMN1; SMN2TP53 | |
| SCHEMBL21285497 | 0.82 | MAPT (0.38) | KMT2AMEN1MAPTSMN1; SMN2TP53 | |
| SCHEMBL22801967 | 0.82 | MAPT (0.40) | KMT2AMEN1MAPTSMN1; SMN2TP53 | |
| SCHEMBL21268737 | 0.81 | MAPT (0.39) | KMT2AMEN1MAPTSMN1; SMN2TP53 | |
| SCHEMBL21268747 | 0.79 | PARP1 (0.39) | MAPTSMN1; SMN2ALDH1A1PARP1 | |
| SCHEMBL21268749 | 0.79 | PARP1 (0.39) | MAPTSMN1; SMN2ALDH1A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019158731-A1 | PHARMACEUTICAL 6,5 HETEROBICYCLIC RING DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2019-08-22 | — | — | WO | disclosed |