Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21274072 | 0.88 | ALDH1A1 (0.37) | RET | |
| SCHEMBL21274070 | 0.88 | ALDH1A1 (0.37) | RET | |
| SCHEMBL21285477 | 0.77 | HRH3 (0.39) | HRH3RET | |
| SCHEMBL21285482 | 0.77 | HRH3 (0.39) | HRH3RET | |
| SCHEMBL21274102 | 0.76 | PARP1 (0.35) | HRH3RET | |
| SCHEMBL22801965 | 0.76 | PARP1 (0.35) | HRH3RET | |
| SCHEMBL21273933 | 0.76 | PARP1 (0.35) | HRH3RET | |
| SCHEMBL22801995 | 0.76 | MAPT (0.34) | HSD11B1RET | |
| SCHEMBL22801994 | 0.76 | MAPT (0.34) | HSD11B1RET | |
| SCHEMBL21273936 | 0.75 | AOC3 (0.39) | HRH3RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019158731-A1 | PHARMACEUTICAL 6,5 HETEROBICYCLIC RING DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2019-08-22 | — | — | WO | disclosed |