Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26882424 | 0.89 | HTR2C (0.38) | HTR2C | |
| SCHEMBL22864830 | 0.89 | HTR2C (0.38) | HTR2C | |
| Trifluoroacetic Acid SCHEMBL29855357 | 0.84 | RORC (0.36) | — | |
| SCHEMBL28459073 | 0.82 | HTR2C (0.38) | HTR2C | |
| SCHEMBL27100707 | 0.81 | — | — | |
| SCHEMBL27101594 | 0.78 | L3MBTL1 (0.37) | — | |
| SCHEMBL27101427 | 0.76 | JAK2 (0.38) | — | |
| SCHEMBL25555099 | 0.75 | SMN1; SMN2 (0.41) | HTR2C | |
| SCHEMBL31197604 | 0.75 | SMN1; SMN2 (0.41) | HTR2C | |
| SCHEMBL21285635 | 0.74 | L3MBTL1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019159120-A1 | ARGINASE INHIBITORS AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2019-08-22 | — | — | WO | disclosed |