Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.46 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.35 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.35 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21281443 | 0.88 | HTR7 (0.44) | HTR7PARP1HRH3KCNH2DRD2 | |
| SCHEMBL21281460 | 0.87 | HTR7 (0.45) | HTR7PARP1L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL21274498 | 0.86 | HTR7 (0.43) | HTR7PARP1HRH3DRD2 | |
| SCHEMBL21274474 | 0.86 | PIM1 (0.44) | PARP1HRH3DRD2ALDH1A1 | |
| SCHEMBL21274287 | 0.86 | KCNH2 (0.45) | HTR7PARP1CYP2D6KCNH2DRD2 | |
| SCHEMBL21274193 | 0.85 | DRD2 (0.48) | HTR7HRH3POLBL3MBTL1DRD2 | |
| SCHEMBL21274001 | 0.85 | CHKA (0.43) | PARP1HRH3CYP1A2L3MBTL1CHKA | |
| SCHEMBL21274069 | 0.84 | PARP1 (0.52) | HTR7PARP1HRH3CYP1A2ALDH1A1 | |
| SCHEMBL21274094 | 0.84 | PARP1 (0.50) | HTR7PARP1 | |
| SCHEMBL21281583 | 0.83 | PARP1 (0.51) | HTR7PARP1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019158731-A1 | PHARMACEUTICAL 6,5 HETEROBICYCLIC RING DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2019-08-22 | — | — | WO | disclosed |