Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | DPP4 | P27487 | 4/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | PRKACG | P22612 | 1/20 | 0.36 |
| ▸ | PRKACB | P22694 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1492704 | 0.78 | MAOB (1.00) | MAOAMAOBTAAR1DPP4SLC6A3 | |
| Water SCHEMBL7260926 | 0.76 | DPP4 (0.88) | MAOAMAOBTAAR1DPP4SLC6A3 | |
| Hydrochloric Acid SCHEMBL6813615 | 0.76 | MAOB (0.95) | MAOAMAOBTAAR1DPP4SLC6A3 | |
| SCHEMBL294582 | 0.74 | DPP4 (1.00) | MAOAMAOBTAAR1DPP4SLC6A3 | |
| SCHEMBL294970 | 0.74 | DPP4 (0.91) | MAOAMAOBTAAR1DPP4SLC6A3 | |
| SCHEMBL21287848 | 0.74 | OPRM1 (0.49) | — | |
| SCHEMBL18461559 | 0.74 | OPRL1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL6809124 | 0.72 | DPP4 (0.88) | MAOAMAOBTAAR1DPP4SLC6A3 | |
| SCHEMBL294761 | 0.72 | DPP4 (0.96) | MAOAMAOBTAAR1DPP4SLC6A3 | |
| Hydrochloric Acid SCHEMBL6809143 | 0.72 | DPP4 (0.96) | MAOAMAOBTAAR1DPP4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019158019-A1 | PYRIMIDINE-FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海青煜医药科技有限公司 | 2019-08-22 | — | — | WO | disclosed |