Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 12/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21287848 | 0.78 | OPRM1 (0.49) | OPRL1OPRM1OPRD1 | |
| SCHEMBL10060840 | 0.75 | OPRL1 (0.68) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL7815717 | 0.75 | OPRL1 (0.68) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL21287129 | 0.74 | MAOA (0.61) | — | |
| SCHEMBL1724862 | 0.71 | OPRL1 (0.57) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL1109741 | 0.71 | OPRL1 (0.57) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL1040024 | 0.69 | OPRL1 (0.55) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL60129 | 0.69 | OPRL1 (0.55) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL29195226 | 0.69 | OPRL1 (0.55) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL13605139 | 0.69 | OPRL1 (0.61) | OPRL1OPRM1OPRK1OPRD1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017017630-A1 | NOVEL BETULINIC SUBSTITUTED AMIDE DERIVATIVES AS HIV INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2017-02-02 | — | — | WO | disclosed |