Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21290148 | 0.81 | ACACA (0.70) | L3MBTL1KDM4ELMNAALDH1A1GAA | |
| SCHEMBL15075259 | 0.80 | L3MBTL1 (1.00) | L3MBTL1KDM4ELMNAALDH1A1GAA | |
| SCHEMBL21289974 | 0.79 | ACACA (0.48) | L3MBTL1KDM4ELMNAALDH1A1GAA | |
| SCHEMBL23956222 | 0.78 | NPC1 (0.67) | L3MBTL1KDM4ELMNAALDH1A1POLB | |
| SCHEMBL21496288 | 0.77 | L3MBTL1 (0.59) | L3MBTL1KDM4ELMNAALDH1A1GAA | |
| SCHEMBL23956341 | 0.77 | L3MBTL1 (0.55) | L3MBTL1KDM4ELMNAALDH1A1GAA | |
| SCHEMBL11619723 | 0.76 | L3MBTL1 (0.62) | L3MBTL1KDM4ELMNAALDH1A1GAA | |
| SCHEMBL21289787 | 0.76 | L3MBTL1 (0.75) | L3MBTL1KDM4ELMNAALDH1A1GAA | |
| SCHEMBL16981107 | 0.73 | L3MBTL1 (0.69) | L3MBTL1KDM4ELMNAALDH1A1GAA | |
| SCHEMBL21290393 | 0.73 | ERN1 (0.46) | L3MBTL1KDM4EALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752512-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-03-01 | — | — | EP | disclosed |
| EP-3601304-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2021-10-27 | — | — | EP | disclosed |
| WO-2019158453-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-08-22 | — | — | WO | disclosed |