Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | FUCA1 | P04066 | 9/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27282454 | 1.00 | HTR1A (0.43) | HTR1ACA1CA2CA4S1PR1 | |
| SCHEMBL27282458 | 1.00 | HTR1A (0.43) | HTR1ACA1CA2CA4S1PR1 | |
| SCHEMBL14130591 | 0.96 | HTR1A (0.46) | HTR1ACA1CA2CA4S1PR1 | |
| SCHEMBL23471349 | 0.88 | FUCA1 (0.49) | HTR1AS1PR1S1PR3FUCA1 | |
| SCHEMBL16511592 | 0.88 | FUCA1 (0.49) | HTR1AS1PR1S1PR3FUCA1 | |
| SCHEMBL9740250 | 0.83 | HTR1A (0.51) | HTR1ACA1CA2CA4S1PR1 | |
| SCHEMBL20351139 | 0.82 | — | — | |
| SCHEMBL8441951 | 0.82 | — | — | |
| SCHEMBL15317987 | 0.82 | — | — | |
| SCHEMBL16748087 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081311-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2024-04-18 | — | — | WO | disclosed |
| WO-2019160882-A1 | PD-1/PD-L1 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2019-08-22 | — | — | WO | disclosed |