Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FUCA1 | P04066 | 5/20 | 0.35 |
| ▸ | MGAM | O43451 | 2/20 | 0.34 |
| ▸ | SI | P14410 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27282454 | 0.96 | HTR1A (0.43) | HTR1ACA1CA2CA4S1PR1 | |
| SCHEMBL21290460 | 0.96 | HTR1A (0.43) | HTR1ACA1CA2CA4S1PR1 | |
| SCHEMBL27282458 | 0.96 | HTR1A (0.43) | HTR1ACA1CA2CA4S1PR1 | |
| SCHEMBL9740250 | 0.88 | HTR1A (0.51) | HTR1ACA1CA2CA4S1PR1 | |
| SCHEMBL28832843 | 0.86 | S1PR1 (0.54) | HTR1AS1PR1S1PR3FUCA1 | |
| SCHEMBL8887602 | 0.84 | S1PR1 (0.56) | HTR1AS1PR1S1PR3FUCA1 | |
| SCHEMBL1517387 | 0.84 | S1PR1 (0.41) | HTR1ACA1S1PR1S1PR3EPHX1 | |
| SCHEMBL23471349 | 0.83 | FUCA1 (0.49) | HTR1AS1PR1S1PR3FUCA1 | |
| SCHEMBL16511592 | 0.83 | FUCA1 (0.49) | HTR1AS1PR1S1PR3FUCA1 | |
| SCHEMBL25590453 | 0.83 | S1PR1 (0.55) | HTR1AS1PR1S1PR3EPHX1FUCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102046597-B | (hetero) arylcyclohexane derivatives | GRUENENTHAL GMBH | 2013-09-11 | — | — | CN | claimed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| CN-102046597-B | (hetero) arylcyclohexane derivatives | GRUENENTHAL GMBH | 2013-09-11 | — | — | CN | disclosed |
| CN-102046597-A | (hetero) arylcyclohexane derivatives | GRUENENTHAL GMBH | 2011-05-04 | — | — | CN | disclosed |
| US-7393887-B2 | Stabilizer system for stabilizing halogen-containing polymers | CROMPTON CORPORATION (US) | 2008-07-01 | — | — | US | disclosed |