SCHEMBL21290634

SCHEMBL21290634

C#CCOCCOCCCCC(CCC(=O)NCCOCCOCC#C)(CCC(=O)NCCOCCOCC#C)NC(=O)CCCC=O

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22223443 0.89 L3MBTL1 (0.36) L3MBTL1
SCHEMBL25976533 0.84 TSHR (0.38) TSHRL3MBTL1
SCHEMBL24840965 0.83 L3MBTL1 (0.31) L3MBTL1
SCHEMBL24759892 0.83 TSHR (0.43) TSHRL3MBTL1
SCHEMBL21291271 0.82 TSHR (0.48) TSHRL3MBTL1
SCHEMBL24588486 0.82 L3MBTL1 (0.45) TSHRL3MBTL1
SCHEMBL24840970 0.82 L3MBTL1 (0.38) TSHRL3MBTL1
SCHEMBL21290595 0.82 GAA (0.36) TSHRL3MBTL1
SCHEMBL25344641 0.81 TSHR (0.47) TSHRL3MBTL1
SCHEMBL21291226 0.81 L3MBTL1 (0.44) TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019161213-A1 TRIALKYNE LINKING AGENTS AND METHODS OF USE Arrowhead Pharmaceuticals, Inc. (US) 2019-08-22 WO disclosed