SCHEMBL24840970

SCHEMBL24840970

C#CCOCCOCCNC(=O)CCC(CCC(=O)NCCOCCOCC#C)(CCC(=O)NCCOCCOCC#C)NC(=O)CCCC(N)=O

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 2/20 0.35
SLC9A3 P48764 3/20 0.33
CA12 O43570 4/20 0.32
CA1 P00915 4/20 0.32
CA2 P00918 4/20 0.32
CA4 P22748 4/20 0.32
CA9 Q16790 4/20 0.32
CA14 Q9ULX7 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21291271 0.91 TSHR (0.48) L3MBTL1TSHRSLC9A3
SCHEMBL24840965 0.89 L3MBTL1 (0.31) L3MBTL1
SCHEMBL21291226 0.88 L3MBTL1 (0.44) L3MBTL1TSHRSLC9A3
SCHEMBL21290595 0.88 GAA (0.36) L3MBTL1TSHRSLC9A3
SCHEMBL24588486 0.88 L3MBTL1 (0.45) L3MBTL1TSHRSLC9A3
SCHEMBL21290649 0.87 L3MBTL1 (0.43) L3MBTL1TSHRSLC9A3
SCHEMBL25344641 0.87 TSHR (0.47) L3MBTL1TSHRSLC9A3
SCHEMBL24759892 0.86 TSHR (0.43) L3MBTL1TSHRSLC9A3
SCHEMBL24759042 0.85 L3MBTL1 (0.41) L3MBTL1TSHRSLC9A3
SCHEMBL24759076 0.84 TSHR (0.36) L3MBTL1TSHRSLC9A3CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230002767-A1 RNAi Agents for Inhibiting Expression of Mucin 5AC (MUC5AC), Compositions Thereof, and Methods of Use SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT 2023-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230002767-A1 RNAi Agents for Inhibiting Expression of Mucin 5AC (MUC5AC), Compositions Thereof, and Methods of Use MUC1, ALG1, RNASE1 L3MBTL1 1195/4885TSHR 3694/4885SLC9A3 2262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.