Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA4 | P22748 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25344800 | 0.86 | TSHR (0.40) | TSHRL3MBTL1CA12CA1CA2 | |
| SCHEMBL23178855 | 0.85 | TSHR (0.36) | TSHRL3MBTL1CA12CA1CA2 | |
| SCHEMBL21290612 | 0.84 | TSHR (0.39) | TSHRL3MBTL1CA12CA1CA2 | |
| SCHEMBL24916769 | 0.84 | TSHR (0.39) | TSHRL3MBTL1CA12CA1CA2 | |
| SCHEMBL21290628 | 0.83 | L3MBTL1 (0.39) | TSHRL3MBTL1CA12CA1CA2 | |
| SCHEMBL24759076 | 0.82 | TSHR (0.36) | TSHRL3MBTL1CA12CA1CA2 | |
| SCHEMBL21291226 | 0.81 | L3MBTL1 (0.44) | TSHRL3MBTL1ALDH1A1TAAR1MEN1 | |
| SCHEMBL24840970 | 0.81 | L3MBTL1 (0.38) | TSHRL3MBTL1CA12CA1CA2 | |
| SCHEMBL24588486 | 0.81 | L3MBTL1 (0.45) | TSHRL3MBTL1 | |
| SCHEMBL21290595 | 0.81 | GAA (0.36) | TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019161213-A1 | TRIALKYNE LINKING AGENTS AND METHODS OF USE | Arrowhead Pharmaceuticals, Inc. (US) | 2019-08-22 | — | — | WO | disclosed |