SCHEMBL21291247

SCHEMBL21291247

C=C(O)/C=C\C(=C)C1=CC=C(C(=O)O)CC1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1355407 0.76 TSHR (0.42) LMNATSHR
SCHEMBL21985657 0.71 TSHR (0.43) LMNATSHR
SCHEMBL13802026 0.65 TSHR (0.32) LMNATSHR
SCHEMBL12189662 0.64 TSHR (0.34) LMNATSHR
SCHEMBL9690992 0.64 TSHR (0.36) LMNATSHR
SCHEMBL24755662 0.64 TSHR (0.34) LMNATSHR
SCHEMBL21264412 0.64 TSHR (0.34) LMNATSHR
SCHEMBL17993483 0.64 TSHR (0.34) LMNATSHR
SCHEMBL24718620 0.63 LMNA (0.31) LMNATSHR
SCHEMBL14754410 0.63 TSHR (0.36) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019161213-A1 TRIALKYNE LINKING AGENTS AND METHODS OF USE Arrowhead Pharmaceuticals, Inc. (US) 2019-08-22 WO disclosed