SCHEMBL21291925

SCHEMBL21291925

CCC(OCc1ccccc1)OP(=O)(O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
CETP P11597 3/20 0.44
PDPK1 O15530 1/20 0.44
MTOR P42345 1/20 0.44
SLC1A3 P43003 2/20 0.41
SLC1A2 P43004 2/20 0.41
SLC1A1 P43005 2/20 0.41
MEN1 O00255 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
KMT2A Q03164 1/20 0.41
ALPG P10696 1/20 0.41
PTK2B Q14289 1/20 0.41
FOLH1 Q04609 1/20 0.40
RCE1 Q9Y256 1/20 0.40
LAP3 P28838 2/20 0.40
ALDH1A1 P00352 1/20 0.40
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21291957 0.90 TSHR (0.51) TSHRCETPPDPK1MTORSLC1A3
SCHEMBL29143318 0.84 TSHR (0.45) TSHRCETPPDPK1MTORALPG
SCHEMBL3079998 0.80 TSHR (0.48) TSHRSLC1A3SLC1A2SLC1A1MEN1
SCHEMBL2874130 0.77 TSHR (0.44) TSHRSLC1A3SLC1A2SLC1A1MEN1
SCHEMBL21291946 0.77 SRC (0.46) TSHRCYP2C9CYP2C19LAP3ALDH1A1
SCHEMBL28232711 0.77 TSHR (0.50) TSHRCETPPDPK1MTORSLC1A3
SCHEMBL21677653 0.75 RCE1 (0.49) TSHRSLC1A3SLC1A2SLC1A1MEN1
SCHEMBL2125892 0.75 TSHR (0.49) TSHRCETPPDPK1MTORSLC1A3
SCHEMBL17471375 0.75 ALDH1A1 (0.53) TSHRCETPSLC1A3SLC1A2SLC1A1
SCHEMBL15441202 0.74 SLC1A3 (0.42) TSHRSLC1A3SLC1A2SLC1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11248011-B2 Phosphorus-based releasing agent, optical polymerizable composition comprising same and preparation thereof SKC CO., LTD. (KR) 2022-02-15 US claimed
CN-110183603-A Phosphorous release agent, including its optics polymerizable composition, polymerizable composition and preparation method thereof SKC株式会社 2019-08-30 CN claimed
US-20190263846-A1 PHOSPHORUS-BASED RELEASING AGENT, OPTICAL POLYMERIZABLE COMPOSITION COMPRISING SAME AND PREPARATION THEREOF SK PUCORE CO., LTD. (KR) 2019-08-29 US claimed
EP-3530684-A1 PHOSPHORUS-BASED RELEASING AGENT, OPTICAL POLYMERIZABLE COMPOSITION COMPRISING SAME AND PREPARATION THEREOF SKC Co., Ltd. (KR) 2019-08-28 EP claimed
CN-110183603-B Phosphorus-containing release agent, optical polymerizable composition containing same, and method for producing same SKC株式会社 2023-04-07 CN disclosed
US-11248011-B2 Phosphorus-based releasing agent, optical polymerizable composition comprising same and preparation thereof SKC CO., LTD. (KR) 2022-02-15 US disclosed
CN-110183603-A Phosphorous release agent, including its optics polymerizable composition, polymerizable composition and preparation method thereof SKC株式会社 2019-08-30 CN disclosed
US-20190263846-A1 PHOSPHORUS-BASED RELEASING AGENT, OPTICAL POLYMERIZABLE COMPOSITION COMPRISING SAME AND PREPARATION THEREOF SK PUCORE CO., LTD. (KR) 2019-08-29 US disclosed
EP-3530684-A1 PHOSPHORUS-BASED RELEASING AGENT, OPTICAL POLYMERIZABLE COMPOSITION COMPRISING SAME AND PREPARATION THEREOF SKC Co., Ltd. (KR) 2019-08-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190263846-A1 PHOSPHORUS-BASED RELEASING AGENT, OPTICAL POLYMERIZABLE COMPOSITION COMPRISING SAME AND PREPARATION THEREOF PMM2, PGM2, IPMK TSHR 4018/4885CETP 1815/4885PDPK1 753/4885
US-11248011-B2 Phosphorus-based releasing agent, optical polymerizable composition comprising same and preparation thereof PMM2, PGM2, IPMK TSHR 4018/4885CETP 1815/4885PDPK1 753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.