Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.48 |
| ▸ | ITGAL | P20701 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21292889 | 1.00 | HTR2A (0.61) | HTR2AMTNR1AMTNR1BGFERHSD17B10 | |
| SCHEMBL21292855 | 0.85 | HTR2A (0.61) | HTR2AMTNR1AMTNR1BGPR84TSHR | |
| SCHEMBL20242715 | 0.85 | HTR2A (0.61) | HTR2AMTNR1AMTNR1BGPR84TSHR | |
| SCHEMBL20425196 | 0.85 | HTR2A (0.61) | HTR2AMTNR1AMTNR1BGPR84TSHR | |
| SCHEMBL21310063 | 0.83 | HTR2A (0.54) | HTR2AMTNR1AMTNR1BGFERHSD17B10 | |
| SCHEMBL30180785 | 0.83 | HTR2A (0.54) | HTR2AMTNR1AMTNR1BGFERHSD17B10 | |
| SCHEMBL28507315 | 0.83 | HTR2A (0.54) | HTR2AMTNR1AMTNR1BGFERHSD17B10 | |
| SCHEMBL27220752 | 0.82 | HTR2B (0.63) | HTR2AMTNR1AMTNR1BHSD17B10GPR84 | |
| SCHEMBL21292933 | 0.82 | HTR2B (0.63) | HTR2AMTNR1AMTNR1BHSD17B10GPR84 | |
| SCHEMBL21292935 | 0.82 | HTR2B (0.63) | HTR2AMTNR1AMTNR1BHSD17B10GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039846-A1 | COMPOUNDS AND METHODS OF USE | FERRO THERAPEUTICS INC (US) | 2023-02-09 | — | — | US | disclosed |
| US-20190263802-A1 | COMPOUNDS AND METHOD OF USE | MOLECULAR SKIN THERAPEUTICS, INC. | 2019-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039846-A1 | COMPOUNDS AND METHODS OF USE | AIFM2, GPX4, GPX1 | HTR2A 3134/4885MTNR1A 2332/4885MTNR1B 1738/4885 |
| US-20190263802-A1 | COMPOUNDS AND METHOD OF USE | AIFM2, GPX4, GPX1 | HTR2A 3059/4885MTNR1A 2360/4885MTNR1B 1677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.