Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.69 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.69 |
| ▸ | LTA4H | P09960 | 1/20 | 0.69 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.61 |
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | HTR2A | P28223 | 2/20 | 0.61 |
| ▸ | HTR2C | P28335 | 2/20 | 0.61 |
| ▸ | HTR2B | P41595 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19666078 | 1.00 | KMT2A (0.69) | KMT2AMEN1HSP90AA1HSP90AB1LTA4H | |
| SCHEMBL19666080 | 1.00 | KMT2A (0.69) | KMT2AMEN1HSP90AA1HSP90AB1LTA4H | |
| Hydrochloric Acid SCHEMBL21292898 | 0.99 | KMT2A (0.68) | KMT2AMEN1HSP90AA1HSP90AB1LTA4H | |
| Hydrochloric Acid SCHEMBL21292896 | 0.99 | KMT2A (0.68) | KMT2AMEN1HSP90AA1HSP90AB1LTA4H | |
| SCHEMBL21310046 | 0.88 | KMT2A (0.54) | KMT2AMEN1HSP90AA1HSP90AB1LTA4H | |
| SCHEMBL28511262 | 0.88 | KMT2A (0.54) | KMT2AMEN1HSP90AA1HSP90AB1LTA4H | |
| Hydrochloric Acid SCHEMBL30181016 | 0.87 | KMT2A (0.53) | KMT2AMEN1HSP90AA1HSP90AB1LTA4H | |
| Hydrochloric Acid SCHEMBL28510961 | 0.87 | KMT2A (0.53) | KMT2AMEN1HSP90AA1HSP90AB1LTA4H | |
| SCHEMBL14301170 | 0.85 | KMT2A (0.73) | KMT2AMEN1HSP90AA1HSP90AB1LTA4H | |
| SCHEMBL30688367 | 0.85 | KMT2A (0.73) | KMT2AMEN1HSP90AA1HSP90AB1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023092133-A1 | STEREOSELECTIVE COVALENT LIGANDS FOR ONCOGENIC AND IMMUNOLOGICAL PROTEINS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-05-25 | — | — | WO | disclosed |
| US-20230039846-A1 | COMPOUNDS AND METHODS OF USE | FERRO THERAPEUTICS INC (US) | 2023-02-09 | — | — | US | disclosed |
| US-20190263802-A1 | COMPOUNDS AND METHOD OF USE | MOLECULAR SKIN THERAPEUTICS, INC. | 2019-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039846-A1 | COMPOUNDS AND METHODS OF USE | AIFM2, GPX4, GPX1 | KMT2A 2510/4885MEN1 1772/4885HSP90AA1 452/4885 |
| US-20190263802-A1 | COMPOUNDS AND METHOD OF USE | AIFM2, GPX4, GPX1 | KMT2A 2475/4885MEN1 1681/4885HSP90AA1 533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.