Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8196213 | 0.98 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4HTT | |
| Hydrochloric Acid SCHEMBL28563692 | 0.98 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4HTT | |
| Hydrochloric Acid SCHEMBL10361599 | 0.98 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4HTT | |
| Hydrochloric Acid SCHEMBL7621998 | 0.98 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4HTT | |
| Hydrochloric Acid SCHEMBL7619758 | 0.98 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4HTT | |
| Hydrochloric Acid SCHEMBL7617842 | 0.98 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4HTT | |
| SCHEMBL21294056 | 0.98 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4HTT | |
| SCHEMBL5693523 | 0.97 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4HTT | |
| SCHEMBL9480136 | 0.97 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4HTT | |
| SCHEMBL9485642 | 0.97 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250355378-A1 | TONER AND METHOD OF MANUFACTURING TONER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2025-11-20 | — | — | US | disclosed |
| CN-110412839-B | Positively chargeable toner, image forming apparatus, and image forming method | 京瓷办公信息系统株式会社 | 2023-08-18 | — | — | CN | disclosed |
| US-20200117107-A1 | POSITIVELY CHARGEABLE TONER, IMAGE FORMING APPARATUS, AND IMAGE FORMATION METHOD | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2020-04-16 | — | — | US | disclosed |
| US-10564559-B2 | Positively chargeable toner, image forming apparatus and image forming method | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2020-02-18 | — | — | US | disclosed |
| US-10474048-B2 | Toner | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2019-11-12 | — | — | US | disclosed |
| US-20190332026-A1 | POSITIVELY CHARGEABLE TONER, IMAGE FORMING APPARATUS AND IMAGE FORMING METHOD | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2019-10-31 | — | — | US | disclosed |
| US-20190265604-A1 | TONER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2019-08-29 | — | — | US | disclosed |
| US-20160193181-A1 | AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA INC. | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160193181-A1 | AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | PDE6D, CLN6, AADAT | ACHE 866/4885TSHR 1801/4885HPGD 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.