Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20672958 | 1.00 | PPARA (0.63) | PPARASLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL9629906 | 0.88 | TDP1 (0.59) | SLC6A2SLC6A3KMT2ATDP1LMNA | |
| SCHEMBL51012 | 0.87 | KMT2A (0.71) | SLC6A2SLC6A3KMT2ATDP1LMNA | |
| SCHEMBL1171933 | 0.86 | FFAR1 (0.67) | PPARAFFAR1HTTALBFFAR4 | |
| SCHEMBL1799635 | 0.86 | FFAR1 (0.67) | PPARAFFAR1HTTALBFFAR4 | |
| SCHEMBL1171526 | 0.86 | FFAR1 (0.67) | PPARAFFAR1HTTALBFFAR4 | |
| SCHEMBL20830500 | 0.85 | TSHR (0.62) | SLC6A2SLC6A3KMT2ATDP1LMNA | |
| SCHEMBL20830910 | 0.85 | TSHR (0.65) | SLC6A2SLC6A3KMT2ATDP1LMNA | |
| SCHEMBL21980210 | 0.84 | LMNA (0.49) | PPARASLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL9780443 | 0.84 | SLC6A2 (0.55) | SLC6A2SLC6A3KMT2ATDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787837-B2 | DCHBS-active esters of PEG compounds and their use | NOVO NORDISK A/S (DK) | 2023-10-17 | — | — | US | disclosed |
| CN-109922835-B | DCHBS active ester of PEG compound and application thereof | 诺和诺德股份有限公司 | 2023-08-04 | — | — | CN | disclosed |
| WO-2022090448-A1 | NOVEL ACYLATING REAGENTS | NOVO NORDISK A/S (DK) | 2022-05-05 | — | — | WO | disclosed |
| EP-3534962-B1 | DCHBS-ACTIVE ESTERS OF PEG COMPOUNDS AND THEIR USE | NOVO NORDISK AS (DK) | 2020-08-19 | — | — | EP | disclosed |
| EP-3534962-A1 | DCHBS-ACTIVE ESTERS OF PEG COMPOUNDS AND THEIR USE | Novo Nordisk A/S (DK) | 2019-09-11 | — | — | EP | disclosed |
| US-20190263854-A1 | DCHBS-ACTIVE ESTERS OF PEG COMPOUNDS AND THEIR USE | NOVO NORDISK A/S (DK) | 2019-08-29 | — | — | US | disclosed |
| CN-109922835-A | The PEGylated DCHBS active ester and application thereof for closing object | 诺和诺德股份有限公司 | 2019-06-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190263854-A1 | DCHBS-ACTIVE ESTERS OF PEG COMPOUNDS AND THEIR USE | HBB, IAPP, GLP1R | PPARA 284/4885SLC6A2 4410/4885SLC6A3 3820/4885 |
| US-11787837-B2 | DCHBS-active esters of PEG compounds and their use | HBB, IAPP, GLP1R | PPARA 284/4885SLC6A2 4410/4885SLC6A3 3820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.