SCHEMBL21294324

SCHEMBL21294324

COCCOC(=O)/C=C/c1ccc(OC)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.72
TDP1 Q9NUW8 2/20 0.72
SMN1; SMN2 Q16637 1/20 0.67
GSK3B P49841 2/20 0.61
F3 P13726 2/20 0.60
THRB P10828 1/20 0.58
ATM Q13315 1/20 0.58
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
MAPT P10636 1/20 0.56
CASP3 P42574 1/20 0.55
SENP7 Q9BQF6 1/20 0.55
SENP6 Q9GZR1 1/20 0.55
GAA P10253 1/20 0.55
HDAC3 O15379 1/20 0.55
HDAC1 Q13547 1/20 0.55
HDAC2 Q92769 1/20 0.55
HDAC8 Q9BY41 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
RAB9A P51151 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8428924 0.88 LMNA (0.65) LMNATDP1SMN1; SMN2GSK3BF3
SCHEMBL8428926 0.88 LMNA (0.65) LMNATDP1SMN1; SMN2GSK3BF3
SCHEMBL8148439 0.88 LMNA (0.68) LMNATDP1SMN1; SMN2GSK3BF3
SCHEMBL39355 0.88 LMNA (0.72) LMNATDP1SMN1; SMN2GSK3BF3
SCHEMBL28067645 0.88 LMNA (0.75) LMNATDP1SMN1; SMN2GSK3BF3
SCHEMBL7890638 0.88 LMNA (0.72) LMNATDP1SMN1; SMN2GSK3BF3
SCHEMBL5259323 0.88 LMNA (0.72) LMNATDP1SMN1; SMN2GSK3BF3
SCHEMBL39354 0.88 LMNA (0.72) LMNATDP1SMN1; SMN2GSK3BF3
Cinoxate SCHEMBL318972 0.87 LMNA (0.67) LMNATDP1SMN1; SMN2GSK3BF3
Cinoxate SCHEMBL1907002 0.87 LMNA (0.67) LMNATDP1SMN1; SMN2GSK3BF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190262252-A1 OIL BASED COMPOSITION AND OIL BASED COSMETIC SHISEIDO COMPANY, LTD. (JP) 2019-08-29 US disclosed