SCHEMBL39354

SCHEMBL39354

CCCOC(=O)/C=C/c1ccc(OC)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.72
TDP1 Q9NUW8 2/20 0.72
SMN1; SMN2 Q16637 1/20 0.67
APP P05067 2/20 0.62
GSK3B P49841 1/20 0.61
ALOX5 P09917 1/20 0.61
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
F3 P13726 2/20 0.60
MAPT P10636 1/20 0.60
THRB P10828 1/20 0.58
ATM Q13315 1/20 0.58
KDM4E B2RXH2 1/20 0.57
CASP3 P42574 1/20 0.55
SENP7 Q9BQF6 1/20 0.55
SENP6 Q9GZR1 1/20 0.55
GAA P10253 1/20 0.55
HDAC3 O15379 1/20 0.55
HDAC1 Q13547 1/20 0.55
HDAC2 Q92769 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39355 1.00 LMNA (0.72) LMNATDP1SMN1; SMN2APPGSK3B
SCHEMBL28433339 0.98 LMNA (0.70) LMNATDP1SMN1; SMN2APPGSK3B
Propionic Acid SCHEMBL27993336 0.94 LMNA (0.65) LMNATDP1SMN1; SMN2APPGSK3B
SCHEMBL4623831 0.92 LMNA (0.73) LMNATDP1SMN1; SMN2APPGSK3B
SCHEMBL1614879 0.92 LMNA (0.73) LMNATDP1SMN1; SMN2APPGSK3B
Cinnamic Acid SCHEMBL20555427 0.91 THRB (0.64) LMNATDP1SMN1; SMN2APPGSK3B
SCHEMBL20943451 0.91 LMNA (0.68) LMNATDP1SMN1; SMN2APPGSK3B
SCHEMBL1614552 0.90 LMNA (0.70) LMNATDP1SMN1; SMN2APPGSK3B
SCHEMBL1614553 0.90 LMNA (0.70) LMNATDP1SMN1; SMN2APPGSK3B
SCHEMBL4070152 0.88 LMNA (0.68) LMNATDP1SMN1; SMN2APPGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1705 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112168722-A Sunscreen essence emulsion capable of effectively resisting ultraviolet injury and preparation method thereof 广州美莱洁化妆品开发有限公司 2021-01-05 CN claimed
US-20180280343-A1 TOPICAL SILIBININ FORMULATIONS AND USES THEREFOR NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2018-10-04 US claimed
US-9232785-B2 Method for reducing sunburn damage in plants BASF SE (DE) 2016-01-12 US claimed
EP-2916814-A1 COMPOSITION CONTAINING A CELLULOSE DERIVED CAPSULE WITH A SUNSCREEN Colabs International Corporation (US) 2015-09-16 EP claimed
US-8748347-B2 Method for combating harmful fungi BASF SE (DE) 2014-06-10 US claimed
WO-2014074555-A1 COMPOSITION CONTAINING A CELLULOSE DERIVED CAPSULE WITH A SUNSCREEN CoLabs International Corporation (US) 2014-05-15 WO claimed
CN-101282708-B External preparation for skin containing a phosphorlated saccharide EZAKI GLICO CO 2013-03-20 CN claimed
EP-2379625-B1 UV AND LIGHT PROTECTIVE FILM HUHTAMAKI FORCHHEIM (DE) 2013-02-20 EP claimed
US-8168227-B2 Modified powder and cosmetic composition using the same SHISEIDO CO., LTD. (JP) 2012-05-01 US claimed
US-20120083497-A1 Method for Combating Harmful Fungi BASF SE (DE) 2012-04-05 US claimed
US-20120017503-A1 METHOD FOR REDUCING SUNBURN DAMAGE IN PLANTS BASF SE (DE) 2012-01-26 US claimed
US-20110083765-A1 UV LIGHT AND PROTECTIVE FILM HUHTAMAKI FORCHHEIM, ZWEIGNIEDERLASSUNG DER HUHTAMAKI DEUTSCHLAND GMBH & CO (DE) 2011-04-14 US claimed
WO-2010115721-A2 METHOD FOR REDUCING SUNBURN DAMAGE IN PLANTS BASF SE (DE) 2010-10-14 WO claimed
WO-2010115720-A2 METHOD FOR COMBATING HARMFUL FUNGI BASF SE (DE) 2010-10-14 WO claimed
EP-1296701-B1 USE OF GRIFOLA FRONDOSA FUNGUS EXTRACTS COGNIS FRANCE SAS (FR) 2009-09-30 EP claimed
US-20070253989-A1 Modified Powder and Cosmetic Composition Using the Same SHISEIDO CO., LTD. (JP) 2007-11-01 US claimed
US-6814959-B1 SOLID AGENTS, COMPRISING POLYMORPHIC LIPID PARTICLES, WITH UV RADIATION-ABSORBING AND/OR REFLECTING ACTION FOR APPLICATION ON THE SKIN, MUCOUS MEMBRANES, SCALP AND HAIR FOR PROTECTION AGAINST HEALTH-DAMAGING UV RADIATION PHARMASOL GMBH (DE) 2004-11-09 US claimed
CN-1372452-A UV radiation reflecting or absorbing agent for protection against harmful UV radiation and for enhancing natural skin barrier PHARMASOL GMBH (DE) 2002-10-02 CN claimed
US-20020131939-A1 Hair protection compositions ROCHE VITAMINS INC. 2002-09-19 US claimed
US-5554374-A Skin preparation using nanospheres COSMETICS DEVELOPMENT COMPANY LIMITED (GB) 1996-09-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120017503-A1 METHOD FOR REDUCING SUNBURN DAMAGE IN PLANTS UNG, ERCC5, ERCC4 LMNA 465/4885TDP1 1081/4885SMN1; SMN2 4542/4885
US-20120083497-A1 Method for Combating Harmful Fungi BROX, CRY1, GUSB LMNA 2775/4885TDP1 1494/4885SMN1; SMN2 4832/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.