Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 5/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.52 |
| ▸ | WDR5 | P61964 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.46 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | C1S | P09871 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720214 | 0.79 | PLA2G10 (0.64) | BLMRECQLKMT2AALDH1A1HPGD | |
| SCHEMBL27878384 | 0.78 | PRSS1 (0.48) | PRSS1PRSS2PRSS3WDR5F10 | |
| SCHEMBL6180080 | 0.78 | PRSS1 (0.48) | PRSS1PRSS2PRSS3WDR5F10 | |
| SCHEMBL394654 | 0.78 | PRSS1 (0.61) | PRSS1PRSS2PRSS3WDR5F10 | |
| SCHEMBL27680541 | 0.76 | PRSS1 (0.69) | PRSS1PRSS2PRSS3WDR5F10 | |
| SCHEMBL29484232 | 0.76 | DPP4 (0.54) | KMT2A | |
| SCHEMBL29484236 | 0.76 | DPP4 (0.54) | KMT2A | |
| SCHEMBL2717268 | 0.75 | PRSS1 (0.70) | PRSS1PRSS2PRSS3F10LOXL2 | |
| SCHEMBL28807346 | 0.75 | WDR5 (0.59) | PRSS1PRSS2PRSS3WDR5F10 | |
| Hydrochloric Acid SCHEMBL28584052 | 0.74 | PRSS1 (0.67) | PRSS1PRSS2PRSS3WDR5F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019161705-A1 | NEW METHOD FOR SYNTHESIZING 1,6-(P-AMIDINOPHENYL)HEXYL DIETHER | 广州同隽医药科技有限公司 | 2019-08-29 | — | — | WO | disclosed |