Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564559 | 0.85 | EPHX2 (0.53) | EPHX2MTNR1AMTNR1BMAPK1GAA | |
| SCHEMBL8564566 | 0.85 | EPHX2 (0.53) | EPHX2MTNR1AMTNR1BMAPK1GAA | |
| SCHEMBL8564568 | 0.85 | EPHX2 (0.53) | EPHX2MTNR1AMTNR1BMAPK1GAA | |
| SCHEMBL17049225 | 0.83 | EPHX2 (0.54) | EPHX2MTNR1AMTNR1BMAPK1GAA | |
| SCHEMBL28791460 | 0.83 | FABP7 (0.43) | EPHX2MTNR1AMTNR1BTACR1ANO1 | |
| SCHEMBL8562145 | 0.80 | MTNR1A (0.56) | EPHX2MTNR1AMTNR1BMAPK1GAA | |
| SCHEMBL8562147 | 0.80 | MTNR1A (0.56) | EPHX2MTNR1AMTNR1BMAPK1GAA | |
| SCHEMBL8562150 | 0.80 | MTNR1A (0.56) | EPHX2MTNR1AMTNR1BMAPK1GAA | |
| SCHEMBL8086570 | 0.79 | MTNR1A (0.50) | EPHX2MTNR1AMTNR1BMAPK1GAA | |
| SCHEMBL9036114 | 0.79 | MTNR1A (0.50) | EPHX2MTNR1AMTNR1BMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116783165-A | 1,2,3, 4-tetrahydroquinoline derivatives as YAP/TAZ-TEAD activation inhibitors for the treatment of cancer | 天主教鲁汶大学 | 2023-09-19 | — | — | CN | disclosed |
| WO-2019161803-A1 | PEPTIDYLARGININE DEIMINASE INHIBITOR AND USE THEREOF | 南京药捷安康生物科技有限公司 | 2019-08-29 | — | — | WO | disclosed |