Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | FABP7 | O15540 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9036114 | 1.00 | MTNR1A (0.50) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL8568310 | 0.86 | CHRNA7 (0.49) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL8568312 | 0.86 | CHRNA7 (0.49) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL8568313 | 0.86 | CHRNA7 (0.49) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL29073380 | 0.86 | MTNR1A (0.49) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL8562150 | 0.86 | MTNR1A (0.56) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL8562145 | 0.86 | MTNR1A (0.56) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL8562147 | 0.86 | MTNR1A (0.56) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL9035962 | 0.85 | MTNR1A (0.49) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL7834187 | 0.84 | GAA (0.44) | MTNR1AMTNR1BEPHX2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823425-B1 | Process for the preparation of an enantiopure tetrahydroquinoline-carboxylic acid | ARCHIMICA SPA (IT) | 2000-10-18 | — | — | EP | claimed |
| EP-0672701-B1 | PNA-synthesis using a base labile aminoprotecting group | HOECHST AG (DE) | 1999-07-28 | — | — | EP | claimed |
| EP-0672701-A1 | PNA-synthesis using a base labile aminoprotecting group | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-20 | — | — | EP | claimed |
| EP-0672701-B1 | PNA-synthesis using a base labile aminoprotecting group | HOECHST AG (DE) | 1999-07-28 | — | — | EP | disclosed |
| EP-0672701-A1 | PNA-synthesis using a base labile aminoprotecting group | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-20 | — | — | EP | disclosed |