Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 6/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RHEB | Q15382 | 2/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | EIF4A3 | P38919 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1244048 | 0.80 | DAO (0.47) | DAOALOX15NFKB1BLMSMN1; SMN2 | |
| SCHEMBL1244642 | 0.80 | DAO (0.47) | DAOGPR35ALOX15NFKB1BLM | |
| SCHEMBL21295056 | 0.79 | ALDH1A1 (0.44) | ALOX15SMN1; SMN2KDM4EHPGD | |
| SCHEMBL1244105 | 0.79 | GRIN1 (0.49) | DAOALOX15NFKB1BLMSMN1; SMN2 | |
| SCHEMBL10826247 | 0.78 | ALDH1A1 (0.43) | SMN1; SMN2 | |
| SCHEMBL1244729 | 0.73 | RHEB (0.46) | DAOGPR35SMN1; SMN2KDM4EHPGD | |
| SCHEMBL10826132 | 0.73 | RAB9A (0.43) | ALOX15NFKB1BLMSMN1; SMN2KDM4E | |
| SCHEMBL1243981 | 0.71 | DAO (0.59) | DAOGPR35ALOX15NFKB1BLM | |
| SCHEMBL1244888 | 0.70 | SRD5A2 (0.42) | DAOGPR35KDM4EHPGDGRIN1 | |
| SCHEMBL3107966 | 0.68 | ALDH1A1 (0.54) | DAOGPR35NFKB1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110194770-B | Peptidyl arginine deiminase inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| WO-2019161803-A1 | PEPTIDYLARGININE DEIMINASE INHIBITOR AND USE THEREOF | 南京药捷安康生物科技有限公司 | 2019-08-29 | — | — | WO | disclosed |