SCHEMBL21295155

SCHEMBL21295155

O=C(O)CC(=O)C1(C(F)F)CC1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.35
SRR Q9GZT4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17816965 0.74
SCHEMBL21272575 0.72 GAA (0.48)
SCHEMBL3816889 0.72
SCHEMBL19900306 0.69 LDHA (0.40) LDHASRR
SCHEMBL16391210 0.65
SCHEMBL22759828 0.65 DGAT1 (0.45)
SCHEMBL18418871 0.65 NPSR1 (0.39)
SCHEMBL21295120 0.64 DGAT1 (0.48) LDHASRR
SCHEMBL18548343 0.64 CYP2C19 (0.34)
SCHEMBL6707961 0.64 FFAR3 (0.50) LDHASRR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4241843-A2 ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS H. Lundbeck A/S (DK) 2023-09-13 EP disclosed
EP-3755684-A1 ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS H. Lundbeck A/S (DK) 2020-12-30 EP disclosed
WO-2019161877-A1 ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS H. LUNDBECK A/S (DK) 2019-08-29 WO disclosed