SCHEMBL21295604

SCHEMBL21295604

[c]1ccc2scc(-c3ccccc3)c2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.35
CYP2A6 P11509 4/20 0.35
ERN1 O75460 3/20 0.34
LMNA P02545 2/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
PRKCZ Q05513 1/20 0.33
CYP17A1 P05093 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2B6 P20813 1/20 0.32
HDAC2 Q92769 1/20 0.32
DAPK3 O43293 1/20 0.32
PRKD3 O94806 1/20 0.32
MAP4K4 O95819 1/20 0.32
ABL1 P00519 1/20 0.32
NTRK1 P04629 1/20 0.32
LCK P06239 1/20 0.32
CSF1R P07333 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21295919 0.86 ERN1 (0.34) MAOBCYP2A6ERN1LMNAMEN1
SCHEMBL28573352 0.84 MAPT (0.41) CYP2A6LMNAALDH1A1HPGDCYP17A1
SCHEMBL28588303 0.81 CYP2A6 (0.45) CYP2A6ALDH1A1CYP17A1CYP1A2CYP2B6
SCHEMBL10324568 0.78 CYP2A6 (0.46) MAOBCYP2A6ERN1ALDH1A1HDAC2
SCHEMBL21295745 0.77 ERN1 (0.42) MAOBCYP2A6ERN1ALDH1A1HDAC2
SCHEMBL5848721 0.77 CYP2A6 (0.52) MAOBCYP2A6ERN1ALDH1A1CYP17A1
SCHEMBL31092063 0.77 CYP2A6 (0.52) MAOBCYP2A6ERN1ALDH1A1CYP17A1
SCHEMBL28583763 0.76 KDM4E (0.38) LMNAMEN1ALDH1A1HPGDKMT2A
SCHEMBL547198 0.73 ADRA2A (0.40)
SCHEMBL5183768 0.73 ACVRL1 (0.33) ACVR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed