SCHEMBL21295652

SCHEMBL21295652

[c]1csc2ccc(-c3ccccc3)cc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F9 P00740 2/20 0.39
PIK3CA P42336 1/20 0.39
PI4KA P42356 1/20 0.39
PI4KB Q9UBF8 1/20 0.39
MAOA P21397 1/20 0.38
ALDH1A1 P00352 3/20 0.37
MEN1 O00255 3/20 0.37
LMNA P02545 3/20 0.37
MAPT P10636 3/20 0.37
KMT2A Q03164 3/20 0.37
HSD17B10 Q99714 2/20 0.37
KDM4E B2RXH2 2/20 0.37
HTT P42858 2/20 0.37
USP2 O75604 1/20 0.37
HSP90AA1 P07900 1/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
TAAR1 Q96RJ0 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21295654 0.85 PIK3CA (0.39) F9PIK3CAPI4KAPI4KBMAOA
SCHEMBL21295618 0.81 PIK3CD (0.46) PIK3CAPI4KAPI4KBLMNAMAPT
SCHEMBL21296093 0.76 PIK3CD (0.48) PIK3CAPI4KAPI4KBALDH1A1LMNA
SCHEMBL206337 0.69 CYP2A6 (0.35) LMNAHSP90AA1CYP2A6
SCHEMBL161023 0.69 KDM4E (0.32) ALDH1A1MAPTKDM4ENPC1RAB9A
SCHEMBL21295607 0.68 PDE3B (0.44) PIK3CAPI4KAPI4KBLMNAMAPT
SCHEMBL6048398 0.67 MAOA (0.43) MAOAALDH1A1MEN1LMNAMAPT
SCHEMBL2022581 0.64 MAOA (0.44) MAOAALDH1A1MEN1LMNAMAPT
SCHEMBL29828944 0.64 LIMK1 (0.51) F9PIK3CAPI4KAPI4KBMAOA
SCHEMBL14296006 0.64 LIMK1 (0.51) F9PIK3CAPI4KAPI4KBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed