SCHEMBL161023

SCHEMBL161023

[c]1csc2cc3ccccc3cc12

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
AR P10275 1/20 0.32
MAPT P10636 1/20 0.32
NFKB1 P19838 1/20 0.32
RAB9A P51151 1/20 0.32
GFER P55789 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
BCL2L1 Q07817 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
NQO2 P16083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4083705 0.96 ALDH1A1 (0.34) KDM4ENPC1ALDH1A1ARMAPT
SCHEMBL15714 0.72
SCHEMBL452120 0.72
Ammonia Solution, Strong SCHEMBL28219894 0.70 GPR3 (0.31) ALDH1A1
SCHEMBL207858 0.67 CYP2A6 (0.39) KDM4ENPC1ALDH1A1MAPTRAB9A
SCHEMBL102590 0.66 CYP2A6 (0.39) KDM4EALDH1A1MAPTCA1CA2
SCHEMBL209040 0.65 CYP2A6 (0.38) KDM4ENPC1ALDH1A1MAPTRAB9A
SCHEMBL207919 0.65 CYP2A6 (0.33) SMN1; SMN2
SCHEMBL206337 0.65 CYP2A6 (0.35)
SCHEMBL9624185 0.65 ESR1 (0.35) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3459 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399200-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS Mitsubishi Gas Chemical Company, Inc. (JP) 2024-07-17 EP claimed
EP-4399199-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS Reuter Chemische Apparatebau e.K. (DE) 2024-07-17 EP claimed
WO-2023213965-A1 INHIBITORS OF CDK8 AND CDK19 UNIVERSITY OF DUNDEE (GB) 2023-11-09 WO claimed
WO-2023038156-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-03-16 WO claimed
WO-2023036868-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2023-03-16 WO claimed
US-11198757-B2 Compositions including a photolatent amine, camphorquinone, and coumarin and related methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-12-14 US claimed
US-11090681-B2 Composition including a polythiol, a polyepoxide, a photolatent base, and an amine and methods relating to the composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-08-17 US claimed
US-20190276588-A1 COMPOSITION INCLUDING A POLYTHIOL, A POLYEPOXIDE, A PHOTOLATENT BASE, AND AN AMINE AND METHODS RELATING TO THE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY 2019-09-12 US claimed
EP-3535333-A1 COMPOSITION INCLUDING A POLYTHIOL, A POLYEPOXIDE, A PHOTOLATENT BASE, AND AN AMINE AND METHODS RELATING TO THE COMPOSITION 3M Innovative Properties Company (US) 2019-09-11 EP claimed
EP-3535621-A1 COMPOSITIONS INCLUDING A PHOTOLATENT AMINE, CAMPHORQUINONE, AND A COUMARIN AND RELATED METHODS 3M Innovative Properties Company (US) 2019-09-11 EP claimed
WO-1999067232-A2 PROCESS FOR THE PREPARATION OF 3-ARYL-BENZOFURANONES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-12-29 WO claimed
WO-1999048997-A1 STABILISATION OF ORGANIC MATERIALS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-09-30 WO claimed
EP-0857765-A2 Stabilizing agents for powder paints Ciba SC Holding AG (CH) 1998-08-12 EP claimed
WO-1998032756-A1 SUBSTITUTED AMINOALKYLIDENAMINO TRIAZINES AS HERBICIDES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-07-30 WO claimed
EP-0842975-A1 Stabilising polyolefins for long term contact with an extracting medium Ciba SC Holding AG (CH) 1998-05-20 EP claimed
EP-0839623-A1 Stabiliser combination for rotomolding process Ciba SC Holding AG (CH) 1998-05-06 EP claimed
US-5652368-A NERVOUS SYSTEM DISORDERS, ALZHEIMER'S DISEASE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1997-07-29 US claimed
US-5607624-A Process for the preparation of 3-arylbenzofuranones CIBA-GEIGY CORPORATION (US) 1997-03-04 US claimed
US-5475007-A Preventing convulsions THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-12-12 US claimed
EP-0648765-A1 Process for the production of 3-arylbenzofuranones CIBA-GEIGY AG (CH) 1995-04-19 EP claimed