SCHEMBL21295848

SCHEMBL21295848

[c]1cc(-c2ccccc2)cc2sccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2E1 P05181 1/20 0.41
CYP2A6 P11509 1/20 0.41
CYP2B6 P20813 1/20 0.41
ALDH1A1 P00352 2/20 0.33
PDPK1 O15530 1/20 0.33
ALOX5 P09917 1/20 0.31
NOTUM Q6P988 1/20 0.31
PIK3CA P42336 1/20 0.31
PI4KA P42356 1/20 0.31
PI4KB Q9UBF8 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
NFKB1 P19838 1/20 0.31
RAB9A P51151 1/20 0.31
NFKB2 Q00653 1/20 0.31
KMT2A Q03164 1/20 0.31
RELA Q04206 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21295654 0.72 PIK3CA (0.39) CYP2E1CYP2A6CYP2B6ALDH1A1ALOX5
SCHEMBL21295836 0.71 KDM4E (0.33) KDM4E
SCHEMBL13472079 0.67 CA12 (0.45) ALDH1A1ALOX5PIK3CAPI4KAPI4KB
SCHEMBL21295772 0.66 CTNNB1 (0.33) CYP2E1CYP2A6CYP2B6ALDH1A1PDPK1
SCHEMBL21295630 0.66 CTNNB1 (0.36) CYP2E1CYP2A6CYP2B6ALDH1A1PDPK1
SCHEMBL1168309 0.65 ESR1 (0.38) ALDH1A1KDM4EMEN1NPC1MAPT
SCHEMBL21295753 0.64 GPR3 (0.43) ALDH1A1PIK3CAPI4KAPI4KBKDM4E
SCHEMBL21295873 0.64 PDPK1 (0.34) PDPK1
SCHEMBL23182 0.63
Biphenyl SCHEMBL347854 0.63 ALDH1A1 (0.43) CYP2E1CYP2A6CYP2B6ALDH1A1PDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed