SCHEMBL21295941

SCHEMBL21295941

[c]1cccc2scc(-c3ccccc3)c12

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.33
CYP2B6 P20813 2/20 0.33
MAOB P27338 1/20 0.33
DAPK3 O43293 1/20 0.33
PRKD3 O94806 1/20 0.33
MAP4K4 O95819 1/20 0.33
ABL1 P00519 1/20 0.33
NTRK1 P04629 1/20 0.33
LCK P06239 1/20 0.33
CSF1R P07333 1/20 0.33
RET P07949 1/20 0.33
MET P08581 1/20 0.33
PDGFRB P09619 1/20 0.33
FGFR1 P11362 1/20 0.33
PDGFRA P16234 1/20 0.33
PRKACA P17612 1/20 0.33
FLT1 P17948 1/20 0.33
LTK P29376 1/20 0.33
KDR P35968 1/20 0.33
MAP2K2 P36507 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21295804 0.86 RAB9A (0.38) FGFR1PRKACAKDRGSK3BRPS6KA3
SCHEMBL21295812 0.80 DYRK1A (0.45) CYP2A6CYP2B6DYRK1ADYRK1BCYP2E1
SCHEMBL6449781 0.80 CYP2A6 (0.39) CYP2A6LMNAALDH1A1HPGDMAPT
SCHEMBL28573332 0.75 CYP19A1 (0.41) MEN1KMT2ALMNAALDH1A1HPGD
SCHEMBL8780181 0.72
SCHEMBL7465117 0.72 CYP2A6 (0.39) CYP2A6CYP2B6MAPK9CLK4ALDH1A1
SCHEMBL3483613 0.71 CYP2A6 (0.33) CYP2A6MAPT
SCHEMBL3483400 0.70 CYP2A6 (0.53) CYP2A6ALDH1A1SMN1; SMN2MAPT
SCHEMBL21295628 0.70 CYP17A1 (0.36) CYP2A6CYP2B6DAPK3PRKD3MAP4K4
SCHEMBL21295839 0.70 LIMK1 (0.41) CYP2A6MAPK9CLK4ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed