SCHEMBL21295628

SCHEMBL21295628

[c]1cccc2c(-c3ccccc3)csc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 1/20 0.36
CYP1A2 P05177 1/20 0.36
RAB9A P51151 3/20 0.33
CYP2A6 P11509 2/20 0.33
CYP2B6 P20813 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CASP3 P42574 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
DAPK3 O43293 1/20 0.33
PRKD3 O94806 1/20 0.33
MAP4K4 O95819 1/20 0.33
ABL1 P00519 1/20 0.33
NTRK1 P04629 1/20 0.33
LCK P06239 1/20 0.33
CSF1R P07333 1/20 0.33
RET P07949 1/20 0.33
MET P08581 1/20 0.33
PDGFRB P09619 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28567776 0.86 RAB9A (0.38) CYP17A1CYP1A2RAB9ASMN1; SMN2CDK5
SCHEMBL28570251 0.80 CYP19A1 (0.46) CYP1A2RAB9ACYP2A6CYP2B6DYRK1A
SCHEMBL28570834 0.75 CYP19A1 (0.44) CYP1A2RAB9ASMN1; SMN2CASP3SENP8
SCHEMBL21295846 0.74 BCAT2 (0.40) RAB9ACYP2A6CYP2B6SMN1; SMN2CASP3
SCHEMBL547079 0.74 ERN1 (0.32)
SCHEMBL8028211 0.71 CYP2A6 (0.33) CYP1A2CYP2A6
SCHEMBL21295941 0.70 CYP2A6 (0.33) RAB9ACYP2A6CYP2B6SMN1; SMN2CASP3
SCHEMBL5848721 0.70 CYP2A6 (0.52) CYP17A1CYP1A2CYP2A6ALDH1A1MAPT
SCHEMBL31092063 0.70 CYP2A6 (0.52) CYP17A1CYP1A2CYP2A6ALDH1A1MAPT
SCHEMBL5766614 0.67 ERN1 (0.51) CYP17A1CYP1A2RAB9ACYP2A6SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed