SCHEMBL21295948

SCHEMBL21295948

[c]1cc(-c2ccncc2)c2ccsc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 2/20 0.39
MAPT P10636 3/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
GFER P55789 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
LMNA P02545 2/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
GSK3B P49841 2/20 0.31
DYRK1A Q13627 2/20 0.31
CDC7 O00311 1/20 0.31
MAPK13 O15264 1/20 0.31
DAPK3 O43293 1/20 0.31
ROCK2 O75116 1/20 0.31
MAP4K4 O95819 1/20 0.31
PIM1 P11309 1/20 0.31
GSK3A P49840 1/20 0.31
NEK4 P51957 1/20 0.31
MAPK12 P53778 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21295694 0.82 ALOX5 (0.37) ADRA2AADRA2BCYP2A6
SCHEMBL21295933 0.81 CYP2A6 (0.54) MAPTRAB9ASMN1; SMN2LMNAADRA2A
SCHEMBL21295863 0.76 MAPT (0.38) MAPK14MAPTNPC1RAB9AGFER
SCHEMBL21295674 0.76 MAPK14 (0.39) MAPK14MAPTNPC1RAB9AGFER
SCHEMBL21295768 0.72 KRAS (0.40) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL21295818 0.68 GPR3 (0.38) MAPK14MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL21295655 0.66 KDM4E (0.34) MAPTKDM4EALDH1A1HTT
SCHEMBL13736167 0.66
SCHEMBL28570273 0.66 GPR3 (0.39) MAPTNPC1RAB9AGFERSMN1; SMN2
SCHEMBL21295930 0.66 MAPK14 (0.42) MAPK14MAPTNPC1RAB9AGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed