SCHEMBL21295976

SCHEMBL21295976

[c]1cc(-c2ccccn2)cc2oc3ccccc3c12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.39
HSD17B10 Q99714 7/20 0.39
KDM4E B2RXH2 6/20 0.39
SMN1; SMN2 Q16637 6/20 0.39
RAB9A P51151 6/20 0.39
ALDH1A1 P00352 5/20 0.39
TP53 P04637 5/20 0.39
HPGD P15428 4/20 0.39
CYP1A2 P05177 3/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
MAPT P10636 1/20 0.38
AHR P35869 1/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1B1 Q16678 1/20 0.36
LMNA P02545 3/20 0.36
METAP1 P53582 2/20 0.36
POLB P06746 1/20 0.36
CCR1 P32246 1/20 0.36
CCR5 P51681 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21295770 0.82 KDM4E (0.38) NPC1HSD17B10KDM4ESMN1; SMN2RAB9A
SCHEMBL21295782 0.79 MAPK14 (0.38) NPC1HSD17B10KDM4ESMN1; SMN2RAB9A
SCHEMBL21295659 0.79 NPC1 (0.38) NPC1HSD17B10KDM4ESMN1; SMN2RAB9A
SCHEMBL21295888 0.79 HPGD (0.41) NPC1HSD17B10KDM4ESMN1; SMN2RAB9A
SCHEMBL30531496 0.77 AHR (0.47) NPC1HSD17B10KDM4ESMN1; SMN2RAB9A
SCHEMBL483615 0.77 AHR (0.47) NPC1HSD17B10KDM4ESMN1; SMN2RAB9A
SCHEMBL21295761 0.76 ALDH1A1 (0.42) NPC1HSD17B10KDM4ERAB9AALDH1A1
SCHEMBL17486247 0.74 NPC1 (0.53) NPC1HSD17B10KDM4ESMN1; SMN2RAB9A
SCHEMBL21019565 0.74 AHR (0.44) NPC1HSD17B10KDM4ESMN1; SMN2RAB9A
SCHEMBL15696818 0.74 NPC1 (0.41) NPC1HSD17B10KDM4ESMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed