Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27769610 | 0.89 | LMNA (0.45) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL28305155 | 0.82 | ALDH1A1 (0.57) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL20640391 | 0.80 | ALDH1A1 (0.38) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL25178103 | 0.78 | TSHR (0.50) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL8349861 | 0.78 | TSHR (0.50) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL9304796 | 0.78 | LMNA (0.46) | TSHRLMNAOPRM1 | |
| SCHEMBL25185269 | 0.77 | TSHR (0.54) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL9718843 | 0.77 | TSHR (0.54) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL25178032 | 0.77 | TSHR (0.54) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL23673217 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TDP1CYP3A4TSHRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019163917-A1 | COMPOUND HAVING S1P5 RECEPTOR AGONIST ACTIVITY | 小野薬品工業株式会社 | 2019-08-29 | — | — | WO | disclosed |