Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 7/20 | 0.56 |
| ▸ | KMO | O15229 | 1/20 | 0.51 |
| ▸ | CDK9 | P50750 | 2/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18413537 | 0.79 | DYRK1A (0.58) | DYRK1AKMOCDK9ADORA2AADORA1 | |
| SCHEMBL26260190 | 0.78 | KDM4E (0.57) | PIK3CDPIK3CAPI4KAPIK3CGPI4KB | |
| SCHEMBL26260209 | 0.76 | KDM4E (0.56) | PIK3CDPIK3CAPI4KAPIK3CGPI4KB | |
| SCHEMBL1602484 | 0.76 | DYRK1A (0.69) | DYRK1AKMOCDK9ADORA2AADORA1 | |
| SCHEMBL29445842 | 0.74 | KDM4E (0.63) | PIK3CDPIK3CAPI4KAPIK3CGPI4KB | |
| SCHEMBL730330 | 0.74 | KDM4E (0.63) | PIK3CDPIK3CAPI4KAPIK3CGPI4KB | |
| SCHEMBL21300599 | 0.74 | KDM4E (0.41) | PIK3CDPIK3CAPI4KAPIK3CGPI4KB | |
| SCHEMBL502867 | 0.73 | KDM4E (0.62) | PIK3CDPIK3CAPI4KAPIK3CGPI4KB | |
| SCHEMBL29679578 | 0.73 | KDM4E (0.62) | PIK3CDPIK3CAPI4KAPIK3CGPI4KB | |
| SCHEMBL21295720 | 0.73 | KDM4E (0.38) | DYRK1AKDM4ELMNATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020085319-A1 | CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT | 東ソー株式会社 | 2020-04-30 | — | — | WO | disclosed |
| WO-2019163959-A1 | CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT | 東ソー株式会社 | 2019-08-29 | — | — | WO | disclosed |